Wassum, Kate
Titles
Associate Professor, Psychology
Member, Brain Research Institute
Neuroscience GPB Home Area
Contact Information
Email
kwassum@ucla.edu Phone
Work Phone Number:
(310) 825-5443
Address
Mailing Address:
Franz Hall Room 8548Los Angeles, CA 90095
UNITED STATES
Biography
Our goals are to 1. Elucidate the neural signals and circuits underlying appetitive associative learning and motivated beahvior and 2. To understand how disruptions in these mechanisms can produce the maldaptive behavior that underlies mental illness.Publications
A selected list of publications:
Wassum KM, Greenfield, VY, Linker KE, Maidment NT, Ostlund SB.
Inflated Reward Value in Early Opiate Withdrawal
Addiction Biology,
2014;
.
Tolosa VM, Wassum KM, Maidment NT, Monbouquette HG.
Electrochemically-deposited iridium oxide reference electrode integrated with an electroenzymatic glutamate sensor on a multi-electrode array microprobe,
Biosensors and Bioelectronics,
2013;
.
Wassum KM, Ostlund SB, Loewinger GC, Maidment NT.
Phasic mesolimbic dopamine release tracks reward seeking during expression of Pavlovian-to-instrumental transfer,
Biological Psychiatry,
2013;
.
Wassum KM, Ostlund SB, Maidment NT.
Phasic mesolimbic dopamine signaling precedes and predicts performance of a self-initiated action sequence,
Biological Psychiatry,
2012;
.
Wassum KM, Tolosa VM, Tseng TC, Balleine BW, Monbouquette HG, Maidment NT.
Transient extracellular glutamate events in the basolateral amygdala track reward seeking actions,
Journal of Neuroscience,
2012;
.
Lichtenberg Nina T, Pennington Zachary T, Holley Sandra M, Greenfield Venuz Y, Cepeda Carlos, Levine Michael S, Wassum Kate M
Basolateral Amygdala to Orbitofrontal Cortex Projections Enable
Cue-Triggered Reward Expectations
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2017; 37(35):
8374-8384.
Hersman Sarah, Cushman Jesse, Lemelson Noah, Wassum Kate, Lotfipour Shahrdad, Fanselow Michael S
Optogenetic excitation of cholinergic inputs to hippocampus primes
future contextual fear associations
Scientific reports,
2017; 7(1):
2333.
Lichtenberg Nina T, Wassum Kate M
Amygdala mu-opioid receptors mediate the motivating influence of
cue-triggered reward expectations
The European journal of neuroscience,
2017; 45(3):
381-387.
Ostlund Sean B, Liu Angela T, Wassum Kate M, Maidment Nigel T
Modulation of cue-triggered reward seeking by cholinergic signaling in
the dorsomedial striatum
The European journal of neuroscience,
2017; 45(3):
358-364.
Collins Anne L, Aitken Tara J, Greenfield Venuz Y, Ostlund Sean B, Wassum Kate M
Nucleus Accumbens Acetylcholine Receptors Modulate Dopamine and
Motivation
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
2016; 41(12):
2830-2838.
Wassum Kate M, Greenfield Venuz Y, Linker Kay E, Maidment Nigel T, Ostlund Sean B
Inflated reward value in early opiate withdrawal
Addiction biology,
2016; 21(2):
221-33.
Aitken Tara J, Greenfield Venuz Y, Wassum Kate M
Nucleus accumbens core dopamine signaling tracks the need-based
motivational value of food-paired cues
Journal of neurochemistry,
2016; 136(5):
1026-36.
Malvaez Melissa, Greenfield Venuz Y, Wang Alice S, Yorita Allison M, Feng Lili, Linker Kay E, Monbouquette Harold G, Wassum Kate M
Corrigendum: Basolateral amygdala rapid glutamate release encodes an
outcome-specific representation vital for reward-predictive cues to
selectively invigorate reward-seeking actions
Scientific reports,
2016; 6(5):
20891.
Collins Anne L, Greenfield Venuz Y, Bye Jeffrey K, Linker Kay E, Wang Alice S, Wassum Kate M
Dynamic mesolimbic dopamine signaling during action sequence learning
and expectation violation
Scientific reports,
2016; 6(5):
20231.
Fanselow Michael S, Wassum Kate M
The Origins and Organization of Vertebrate Pavlovian Conditioning
Cold Spring Harbor perspectives in biology,
2015; 8(1):
a021717.
Malvaez Melissa, Greenfield Venuz Y, Wang Alice S, Yorita Allison M, Feng Lili, Linker Kay E, Monbouquette Harold G, Wassum Kate M
Basolateral amygdala rapid glutamate release encodes an
outcome-specific representation vital for reward-predictive cues to
selectively invigorate reward-seeking actions
Scientific reports,
2015; 5:
12511.
Wassum Kate M, Izquierdo Alicia
The basolateral amygdala in reward learning and addiction
Neuroscience and biobehavioral reviews,
2015;
.
Wassum Kate M, Phillips Paul E M
Probing the neurochemical correlates of motivation and decision
making
ACS chemical neuroscience,
2015; 6(1):
11-3.
Ostlund Sean B, LeBlanc Kimberly H, Kosheleff Alisa R, Wassum Kate M, Maidment Nigel T
Phasic mesolimbic dopamine signaling encodes the facilitation of
incentive motivation produced by repeated cocaine exposure
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
2014; 39(10):
2441-9.
Tolosa Vanessa M, Wassum Kate M, Maidment Nigel T, Monbouquette Harold G
Electrochemically deposited iridium oxide reference electrode
integrated with an electroenzymatic glutamate sensor on a
multi-electrode array microprobe
Biosensors & bioelectronics,
2013; 42(8):
256-60.
Wassum Kate M, Ostlund Sean B, Loewinger Gabriel C, Maidment Nigel T
Phasic mesolimbic dopamine release tracks reward seeking during
expression of Pavlovian-to-instrumental transfer
Biological psychiatry,
2013; 73(8):
747-55.
Wassum Kate M, Ostlund Sean B, Maidment Nigel T
Phasic mesolimbic dopamine signaling precedes and predicts performance
of a self-initiated action sequence task
Biological psychiatry,
2012; 71(10):
846-54.
Wassum Kate M, Tolosa Vanessa M, Tseng Tina C, Balleine Bernard W, Monbouquette Harold G, Maidment Nigel T
Transient extracellular glutamate events in the basolateral amygdala
track reward-seeking actions
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2012; 32(8):
2734-46.
Wassum Kate M, Ostlund Sean B, Balleine Bernard W, Maidment Nigel T
Differential dependence of Pavlovian incentive motivation and
instrumental incentive learning processes on dopamine signaling
Learning & memory (Cold Spring Harbor, N.Y.),
2011; 18(7):
475-83.
Wassum Kate M, Cely Ingrid C, Balleine Bernard W, Maidment Nigel T
Micro-opioid receptor activation in the basolateral amygdala mediates
the learning of increases but not decreases in the incentive value of
a food reward
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2011; 31(5):
1591-9.
Ostlund Sean B, Wassum Kate M, Murphy Niall P, Balleine Bernard W, Maidment Nigel T
Extracellular dopamine levels in striatal subregions track shifts in
motivation and response cost during instrumental conditioning
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2011; 31(1):
200-7.
Wassum KM, Cely IC, Ostlund SB, Maidment NT, Balleine BW.
Disruption of endogenous opioid activity during instrumental learning enhances habit acquisition,
Neuroscience,
2009; 163(3):
770-80.
Wassum KM, Ostlund SB, Maidment NT, Balleine BW.
Distinct opioid circuits determine the palatability and the desirability of rewarding events,
Proc Natl Acad Sci USA,
2009; 106(30):
12512-7.
Wassum Kate M, Evans Christopher J
International Narcotics Research Conference - 39th Annual Meeting
IDrugs : the investigational drugs journal,
2008; 11(9):
646-9.
Wassum Kate M, Tolosa Vanessa M, Wang Jianjun, Walker Eric, Monbouquette Harold G, Maidment Nigel T
Silicon Wafer-Based Platinum Microelectrode Array Biosensor for Near
Real-Time Measurement of Glutamate in Vivo
Sensors (Basel, Switzerland),
2008; 8(8):
5023-5036.
Wightman R Mark, Heien Michael L A V, Wassum Kate M, Sombers Leslie A, Aragona Brandon J, Khan Amina S, Ariansen Jennifer L, Cheer Joseph F, Phillips Paul E M, Carelli Regina M
Dopamine release is heterogeneous within microenvironments of the rat
nucleus accumbens
The European journal of neuroscience,
2007; 26(7):
2046-54.
Cheer Joseph F, Wassum Kate M, Sombers Leslie A, Heien Michael L A V, Ariansen Jennifer L, Aragona Brandon J, Phillips Paul E M, Wightman R Mark
Phasic dopamine release evoked by abused substances requires
cannabinoid receptor activation
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2007; 27(4):
791-5.
Cheer Joseph F, Wassum Kate M, Wightman R Mark
Cannabinoid modulation of electrically evoked pH and oxygen transients
in the nucleus accumbens of awake rats
Journal of neurochemistry,
2006; 97(4):
1145-54.
Heien Michael L A V, Khan Amina S, Ariansen Jennifer L, Cheer Joseph F, Phillips Paul E M, Wassum Kate M, Wightman R Mark
Real-time measurement of dopamine fluctuations after cocaine in the
brain of behaving rats
Proceedings of the National Academy of Sciences of the United States of America,
2005; 102(29):
10023-8.
Cheer Joseph F, Wassum Kate M, Heien Michael L A V, Phillips Paul E M, Wightman R Mark
Cannabinoids enhance subsecond dopamine release in the nucleus
accumbens of awake rats
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2004; 24(18):
4393-400.