Leuchter, Andrew
Titles
Director, Quantitative Electroencephalography (QEEG) Laboratory
Professor, Psychiatry and Biobehavioral Sciences
Member, Adult Psychiatry
Brain Research Institute
Neuroscience GPB Home Area
Contact Information
Email
afl@ucla.edu Phone
Work Phone Number:
(310) 825-0207
Address
Mailing Address:
UCLA Semel760 Westwood Plaza, Room 37-452
Los Angeles, CA 90095
UNITED STATES
Publications
A selected list of publications:
Leuchter Andrew F, Hunter Aimee M, Tartter Molly, Cook Ian A
Authors' reply
The British journal of psychiatry : the journal of mental science,
2015; 207(6):
561-2.
Hunter Aimee M, Cook Ian A, Tartter Molly, Sharma Simi K, Disse Gregory D, Leuchter Andrew F
Antidepressant treatment history and drug-placebo separation in a
placebo-controlled trial in major depressive disorder
Psychopharmacology,
2015; 232(20):
3833-40.
Leuchter Andrew F, Cook Ian A, Feifel David, Goethe John W, Husain Mustafa, Carpenter Linda L, Thase Michael E, Krystal Andrew D, Philip Noah S, Bhati Mahendra T, Burke William J, Howland Robert H, Sheline Yvette I, Aaronson Scott T, Iosifescu Dan V, O'Reardon John P, Gilmer William S, Jain Rakesh, Burgoyne Karl S, Phillips Bill, Manberg Paul J, Massaro Joseph, Hunter Aimee M, Lisanby Sarah H, George Mark S
Efficacy and Safety of Low-field Synchronized Transcranial Magnetic
Stimulation (sTMS) for Treatment of Major Depression
Brain stimulation,
2015; 8(4):
787-94.
McGough James J, Loo Sandra K, Sturm Alexandra, Cowen Jennifer, Leuchter Andrew F, Cook Ian A
An eight-week, open-trial, pilot feasibility study of trigeminal nerve
stimulation in youth with attention-deficit/hyperactivity disorder
Brain stimulation,
2015; 8(2):
299-304.
Leuchter Andrew F, Hunter Aimee M, Krantz David E, Cook Ian A
Rhythms and blues: modulation of oscillatory synchrony and the
mechanism of action of antidepressant treatments
Annals of the New York Academy of Sciences,
2015; 1344(4):
78-91.
Leuchter Andrew F, Hunter Aimee M, Krantz David E, Cook Ian A
Intermediate phenotypes and biomarkers of treatment outcome in major
depressive disorder
Dialogues in clinical neuroscience,
2014; 16(4):
525-37.
Leuchter Andrew F, Hunter Aimee M, Tartter Molly, Cook Ian A
Role of pill-taking, expectation and therapeutic alliance in the
placebo response in clinical trials for major depression
The British journal of psychiatry : the journal of mental science,
2014; 205(6):
443-9.
Cook Ian A, Espinoza Randall, Leuchter Andrew F
Neuromodulation for depression: invasive and noninvasive (deep brain
stimulation, transcranial magnetic stimulation, trigeminal nerve
stimulation)
Neurosurgery clinics of North America,
2014; 25(1):
103-16.
Cook Ian A, Schrader Lara M, Degiorgio Christopher M, Miller Patrick R, Maremont Eve R, Leuchter Andrew F
Trigeminal nerve stimulation in major depressive disorder: acute
outcomes in an open pilot study
Epilepsy & behavior : E&B,
2013; 28(2):
221-6.
Hunter Aimee M, Korb Alexander S, Cook Ian A, Leuchter Andrew F
Rostral anterior cingulate activity in major depressive disorder:
state or trait marker of responsiveness to medication?
The Journal of neuropsychiatry and clinical neurosciences,
2013; 25(2):
126-33.
Leuchter Andrew F, Cook Ian A, Jin Yi, Phillips Bill
The relationship between brain oscillatory activity and therapeutic
effectiveness of transcranial magnetic stimulation in the treatment of
major depressive disorder
Frontiers in human neuroscience,
2013; 7(2):
37.
Hunter Aimee M, Cook Ian A, Leuchter Andrew F
Does prior antidepressant treatment of major depression impact brain
function during current treatment?
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
2012;
.
Kerber Kevin Brian, Wisniewski Stephen R, Luther James F, Leuchter Andrew F, D'Empaire Inna, Trivedi Madhukar H, Rush A John
Effects of heart disease on depression treatment: results from the
COMED study
General hospital psychiatry,
2012; 34(1):
24-34.
Leuchter Andrew F, Cook Ian A, Hunter Aimee M, Cai Chaochao, Horvath Steve
Resting-state quantitative electroencephalography reveals increased
neurophysiologic connectivity in depression
PloS one,
2012; 7(2):
e32508.
Hunter Aimee M, Cook Ian A, Greenwald Scott D, Tran Melody L, Miyamoto Kate N, Leuchter Andrew F
The antidepressant treatment response index and treatment outcomes in
a placebo-controlled trial of fluoxetine
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society,
2011; 28(5):
478-82.
Korb Alexander S, Hunter Aimee M, Cook Ian A, Leuchter Andrew F
Rostral anterior cingulate cortex activity and early symptom
improvement during treatment for major depressive disorder
Psychiatry research,
2011; 192(3):
188-94.
Muthén Bengt, Asparouhov Tihomir, Hunter Aimee M, Leuchter Andrew F
Growth modeling with nonignorable dropout: alternative analyses of the
STAR*D antidepressant trial
Psychological methods,
2011; 16(1):
17-33.
Leuchter Andrew F, Cook Ian A, Hamilton Steven P, Narr Katherine L, Toga Arthur, Hunter Aimee M, Faull Kym, Whitelegge Julian, Andrews Anne M, Loo Joseph, Way Baldwin, Nelson Stanley F, Horvath Steven, Lebowitz Barry D
Biomarkers to predict antidepressant response
Current psychiatry reports,
2010; 12(6):
553-62.
Hunter Aimee M, Cook Ian A, Leuchter Andrew F
Impact of antidepressant treatment history on clinical outcomes in
placebo and medication treatment of major depression
Journal of clinical psychopharmacology,
2010; 30(6):
748-51.
Hunter Aimee, Bordelon Yvette, Cook Ian, Leuchter Andrew
QEEG Measures in Huntington's Disease: A Pilot Study
PLoS currents,
2010; 2(6):
RRN1192.
Warden Diane, Trivedi Madhukar H, Wisniewski Stephen R, Kurian Benji, Zisook Sidney, Kornstein Susan G, Friedman Edward S, Miyahara Sachiko, Leuchter Andrew F, Fava Maurizio, Rush A John
Early adverse events and attrition in selective serotonin reuptake
inhibitor treatment: a suicide assessment methodology study report
Journal of clinical psychopharmacology,
2010; 30(3):
259-66.
Kobak Kenneth A, Leuchter Andrew, DeBrota David, Engelhardt Nina, Williams Janet B W, Cook Ian A, Leon Andrew C, Alpert Jonathan
Site versus centralized raters in a clinical depression trial: impact
on patient selection and placebo response
Journal of clinical psychopharmacology,
2010; 30(2):
193-7.
Farahbod Haleh, Cook Ian A, Korb Alexander S, Hunter Aimee M, Leuchter Andrew F
Amygdala lateralization at rest and during viewing of neutral faces in
major depressive disorder using low-resolution brain electromagnetic
tomography
Clinical EEG and neuroscience : official journal of the EEG and Clinical Neuroscience Society (ENCS),
2010; 41(1):
19-23.
Hunter Aimee M, Muthén Bengt O, Cook Ian A, Leuchter Andrew F
Antidepressant response trajectories and quantitative
electroencephalography (QEEG) biomarkers in major depressive disorder
Journal of psychiatric research,
2010; 44(2):
90-8.
Cook Ian A, Hunter Aimee M, Abrams Michelle, Siegman Barbara, Leuchter Andrew F
Midline and right frontal brain function as a physiologic biomarker of
remission in major depression
Psychiatry research,
2009; 174(2):
152-7.
Leuchter Andrew F, Cook Ian A, Marangell Lauren B, Gilmer William S, Burgoyne Karl S, Howland Robert H, Trivedi Madhukar H, Zisook Sidney, Jain Rakesh, McCracken James T, Fava Maurizio, Iosifescu Dan, Greenwald Scott
Comparative effectiveness of biomarkers and clinical indicators for
predicting outcomes of SSRI treatment in Major Depressive Disorder:
results of the BRITE-MD study
Psychiatry research,
2009; 169(2):
124-31.
Leuchter Andrew F, Cook Ian A, Gilmer William S, Marangell Lauren B, Burgoyne Karl S, Howland Robert H, Trivedi Madhukar H, Zisook Sidney, Jain Rakesh, Fava Maurizio, Iosifescu Dan, Greenwald Scott
Effectiveness of a quantitative electroencephalographic biomarker for
predicting differential response or remission with escitalopram and
bupropion in major depressive disorder
Psychiatry research,
2009; 169(2):
132-8.
Leuchter Andrew F, McCracken James T, Hunter Aimee M, Cook Ian A, Alpert Jonathan E
Monoamine oxidase a and catechol-o-methyltransferase functional
polymorphisms and the placebo response in major depressive disorder
Journal of clinical psychopharmacology,
2009; 29(4):
372-7.
Hunter Aimee M, Leuchter Andrew F, Cook Ian A, Abrams Michelle, Siegman Barbara E, Furst Daniel E, Chappell Amy S
Brain functional changes and duloxetine treatment response in
fibromyalgia: a pilot study
Pain medicine (Malden, Mass.),
2009; 10(4):
730-8.
Kalechstein Ari D, De la Garza Richard, Newton Thomas F, Green Michael F, Cook Ian A, Leuchter Andrew F
Quantitative EEG abnormalities are associated with memory impairment
in recently abstinent methamphetamine-dependent individuals
The Journal of neuropsychiatry and clinical neurosciences,
2009; 21(3):
254-8.
Korb Alexander S, Hunter Aimee M, Cook Ian A, Leuchter Andrew F
Rostral anterior cingulate cortex theta current density and response
to antidepressants and placebo in major depression
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
2009; 120(7):
1313-9.
Leuchter Andrew F, Cook Ian A, Hunter Aimee M, Korb Alexander S
A new paradigm for the prediction of antidepressant treatment
response
Dialogues in clinical neuroscience,
2009; 11(4):
435-46.
Leuchter Andrew F, Cook Ian A, Hunter Aimee, Korb Alex
Use of clinical neurophysiology for the selection of medication in the
treatment of major depressive disorder: the state of the evidence
Clinical EEG and neuroscience : official journal of the EEG and Clinical Neuroscience Society (ENCS),
2009; 40(2):
78-83.
Korb Alexander S, Cook Ian A, Hunter Aimee M, Leuchter Andrew F
Brain electrical source differences between depressed subjects and
healthy controls
Brain topography,
2008; 21(2):
138-46.
Leuchter Andrew F, Cook Ian A, DeBrota David J, Hunter Aimee M, Potter William Z, McGrouther Caroline C, Morgan Melinda L, Abrams Michelle, Siegman Barbara
Changes in brain function during administration of venlafaxine or
placebo to normal subjects
Clinical EEG and neuroscience : official journal of the EEG and Clinical Neuroscience Society (ENCS),
2008; 39(4):
175-81.
Leuchter Andrew F, Lesser Ira M, Trivedi Madhukar H, Rush A John, Morris David W, Warden Diane, Fava Maurizio, Wisniewski Stephen R, Luther James F, Perales Mercedes, Gaynes Bradley N, Stewart Jonathan W
An open pilot study of the combination of escitalopram and
bupropion-SR for outpatients with major depressive disorder
Journal of psychiatric practice,
2008; 14(5):
271-80.
Fava Maurizio, Rush A John, Alpert Jonathan E, Balasubramani G K, Wisniewski Stephen R, Carmin Cheryl N, Biggs Melanie M, Zisook Sidney, Leuchter Andrew, Howland Robert, Warden Diane, Trivedi Madhukar H
Difference in treatment outcome in outpatients with anxious versus
nonanxious depression: a STAR*D report
The American journal of psychiatry,
2008; 165(3):
342-51.
Shapiro David, Cook Ian A, Davydov Dmitry M, Ottaviani Cristina, Leuchter Andrew F, Abrams Michelle
Yoga as a Complementary Treatment of Depression: Effects of Traits and
Moods on Treatment Outcome
Evidence-based complementary and alternative medicine : eCAM,
2007; 4(4):
493-502.
Lesser Ira M, Leuchter Andrew F, Trivedi Madhukar H, Davis Lori L, Wisniewski Stephen R, Balasubramani G K, Fava Maurizio, Rush A John
Insured and non-insured depressed outpatients: how do they compare?
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists,
2007; 19(2):
73-82.
Leuchter Andrew, Levey Gerald S
Need to strike balance with industry-academia rules
Nature,
2007; 449(7163):
658.
Cook Ian A, Bookheimer Susan Y, Mickes Laura, Leuchter Andrew F, Kumar Anand
Aging and brain activation with working memory tasks: an fMRI study of
connectivity
International journal of geriatric psychiatry,
2007; 22(4):
332-42.
Hunter Aimee M, Cook Ian A, Leuchter Andrew F
The promise of the quantitative electroencephalogram as a predictor of
antidepressant treatment outcomes in major depressive disorder
The Psychiatric clinics of North America,
2007; 30(1):
105-24.
Claassen Cynthia A, Trivedi Madhukar H, Rush A John, Husain Mustafa M, Zisook Sidney, Young Elizabeth, Leuchter Andrew, Wisniewski Stephen R, Balasubramani G K, Alpert Jonathan
Clinical differences among depressed patients with and without a
history of suicide attempts: findings from the STAR*D trial
Journal of affective disorders,
2007; 97(1-3):
77-84.
Morgan Melinda L, Cook Ian A, Rapkin Andrea J, Leuchter Andrew F
Neurophysiologic changes during estrogen augmentation in
perimenopausal depression
Maturitas,
2007; 56(1):
54-60.
Hunter Aimee M, Leuchter Andrew F, Morgan Melinda L, Cook Ian A
Changes in brain function (quantitative EEG cordance) during placebo
lead-in and treatment outcomes in clinical trials for major
depression
The American journal of psychiatry,
2006; 163(8):
1426-32.
Moses Tally, Leuchter Andrew F, Cook Ian, Abrams Michelle
Does the clinical course of depression determine improvement in
symptoms and quality of life?
The Journal of nervous and mental disease,
2006; 194(4):
241-8.
Venneman Sandy, Leuchter Andrew, Bartzokis George, Beckson Mace, Simon Sara L, Schaefer Melodie, Rawson Richard, Newton Tom, Cook Ian A, Uijtdehaage Sebastian, Ling Walter
Variation in neurophysiological function and evidence of quantitative
electroencephalogram discordance: predicting cocaine-dependent
treatment attrition
The Journal of neuropsychiatry and clinical neurosciences,
2006; 18(2):
208-16.
Cook Ian A, Leuchter Andrew F, Morgan Melinda L, Stubbeman William, Siegman Barbara, Abrams Michelle
Changes in prefrontal activity characterize clinical response in SSRI
nonresponders: a pilot study
Journal of psychiatric research,
2005; 39(5):
461-6.
Krell Heather V, Leuchter Andrew F, Cook Ian A, Abrams Michelle
Evaluation of reboxetine, a noradrenergic antidepressant, for the
treatment of fibromyalgia and chronic low back pain
Psychosomatics,
2005; 46(5):
379-84.
Lesser Ira M, Leuchter Andrew F, Trivedi Madhukar H, Davis Lori L, Wisniewski Stephen R, Balasubramani G K, Petersen Timothy, Stegman Diane, Rush A John
Characteristics of insured and noninsured outpatients with depression
in STAR(*)D
Psychiatric services (Washington, D.C.),
2005; 56(8):
995-1004.
Morgan Melinda L, Cook Ian A, Rapkin Andrea J, Leuchter Andrew F
Estrogen augmentation of antidepressants in perimenopausal depression:
a pilot study
The Journal of clinical psychiatry,
2005; 66(6):
774-80.
Morgan Melinda L, Witte Elise A, Cook Ian A, Leuchter Andrew F, Abrams Michelle, Siegman Barbara
Influence of age, gender, health status, and depression on
quantitative EEG
Neuropsychobiology,
2005; 52(2):
71-6.
Hunter Aimee M, Leuchter Andrew F, Morgan Melinda L, Cook Ian A, Abrams Michelle, Siegman Barbara, DeBrota David J, Potter William Z
Neurophysiologic correlates of side effects in normal subjects
randomized to venlafaxine or placebo
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
2005; 30(4):
792-9.
Leuchter Andrew F, Morgan Melinda, Cook Ian A, Dunkin Jennifer, Abrams Michelle, Witte Elise
Pretreatment neurophysiological and clinical characteristics of
placebo responders in treatment trials for major depression
Psychopharmacology,
2004; 177(1-2):
15-22.
Stubbeman William F, Leuchter Andrew F, Cook Ian A, Shurman Brett D, Morgan Melinda, Gunay Ibrahim, Gonzalez Sergio
Pretreatment neurophysiologic function and ECT response in depression
The journal of ECT,
2004; 20(3):
142-4.
Krell Heather V, Leuchter Andrew F, Morgan Melinda, Cook Ian A, Abrams Michelle
Subject expectations of treatment effectiveness and outcome of
treatment with an experimental antidepressant
The Journal of clinical psychiatry,
2004; 65(9):
1174-9.
Cook Ian A, Leuchter Andrew F, Morgan Melinda L, Dunkin Jennifer J, Witte Elise, David Steven, Mickes Laura, O'Hara Ruth, Simon Sara, Lufkin Robert, Abrams Michelle, Rosenberg Susan
Longitudinal progression of subclinical structural brain disease in
normal aging
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
2004; 12(2):
190-200.
Marie-Mitchell Ariane, Leuchter Andrew F, Chou Chih-Ping, James Gauderman W, Azen Stanley P
Predictors of improved mood over time in clinical trials for major
depression
Psychiatry research,
2004; 127(1-2):
73-84.
Newton Thomas F, Kalechstein Ari D, Hardy David J, Cook Ian A, Nestor Liam, Ling Walter, Leuchter Andrew F
Association between quantitative EEG and neurocognition in
methamphetamine-dependent volunteers
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
2004; 115(1):
194-8.
Newton Thomas F, Cook Ian A, Kalechstein Ari D, Duran Sonia, Monroy Franz, Ling Walter, Leuchter Andrew F
Quantitative EEG abnormalities in recently abstinent methamphetamine
dependent individuals
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
2003; 114(3):
410-5.
Cook Ian A, Leuchter Andrew F, Morgan Melinda L, Conlee Elise Witte, David Steven, Lufkin Robert, Babaie Ashkan, Dunkin Jennifer J, O'Hara Ruth, Simon Sara, Lightner Amy, Thomas Susan, Broumandi David, Badjatia Neeraj, Mickes Laura, Mody Rajal K, Arora Sanjaya, Zheng Zimu, Abrams Michelle, Rosenberg-Thompson Susan
Cognitive and physiologic correlates of subclinical structural brain
disease in elderly healthy control subjects
Archives of neurology,
2002; 59(10):
1612-20.
Cook Ian A, Leuchter Andrew F, Morgan Melinda, Witte Elise, Stubbeman William F, Abrams Michelle, Rosenberg Susan, Uijtdehaage Sebastian H J
Early changes in prefrontal activity characterize clinical responders
to antidepressants
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
2002; 27(1):
120-31.
Cook Ian A, Morgan Melinda L, Dunkin Jennifer J, David Steven, Witte Elise, Lufkin Robert, Abrams Michelle, Rosenberg Susan, Leuchter Andrew F
Estrogen replacement therapy is associated with less progression of
subclinical structural brain disease in normal elderly women: a pilot
study
International journal of geriatric psychiatry,
2002; 17(7):
610-8.
Leuchter Andrew F, Cook Ian A, Witte Elise A, Morgan Melinda, Abrams Michelle
Changes in brain function of depressed subjects during treatment with
placebo
The American journal of psychiatry,
2002; 159(1):
122-9.