de la Torre-Ubieta, Luis
Titles
Assistant Professor, Psychiatry and Biobehavioral Sciences
Member, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
Genetics & Genomics GPB Home Area
Intellectual and Development Disabilities Research Center
Neuroscience GPB Home Area
Contact Information
Email
ldelatorreubieta@mednet.ucla.edu Phone
Work Phone Number:
310-267-5540
Publications
A selected list of publications:
de la Torre-Ubieta Luis, Stein Jason L, Won Hyejung, Opland Carli K, Liang Dan, Lu Daning, Geschwind Daniel H
The Dynamic Landscape of Open Chromatin during Human Cortical
Neurogenesis
Cell,
2018; 172(1-2):
289-304.e18.
Watanabe Momoko, Buth Jessie E, Vishlaghi Neda, de la Torre-Ubieta Luis, Taxidis Jiannis, Khakh Baljit S, Coppola Giovanni, Pearson Caroline A, Yamauchi Ken, Gong Danyang, Dai Xinghong, Damoiseaux Robert, Aliyari Roghiyh, Liebscher Simone, Schenke-Layland Katja, Caneda Christine, Huang Eric J, Zhang Ye, Cheng Genhong, Geschwind Daniel H, Golshani Peyman, Sun Ren, Novitch Bennett G
Self-Organized Cerebral Organoids with Human-Specific Features Predict
Effective Drugs to Combat Zika Virus Infection
Cell reports,
2017; 21(2):
517-532.
Parikshak Neelroop N, Swarup Vivek, Belgard T Grant, Irimia Manuel, Ramaswami Gokul, Gandal Michael J, Hartl Christopher, Leppa Virpi, Ubieta Luis de la Torre, Huang Jerry, Lowe Jennifer K, Blencowe Benjamin J, Horvath Steve, Geschwind Daniel H
Genome-wide changes in lncRNA, splicing, and regional gene expression
patterns in autism
Nature,
2016; 540(7633):
423-427.
Won Hyejung, de la Torre-Ubieta Luis, Stein Jason L, Parikshak Neelroop N, Huang Jerry, Opland Carli K, Gandal Michael J, Sutton Gavin J, Hormozdiari Farhad, Lu Daning, Lee Changhoon, Eskin Eleazar, Voineagu Irina, Ernst Jason, Geschwind Daniel H
Chromosome conformation elucidates regulatory relationships in
developing human brain
Nature,
2016; 538(7626):
523-527.
Chiocchetti A G, Haslinger D, Stein J L, de la Torre-Ubieta L, Cocchi E, Rothämel T, Lindlar S, Waltes R, Fulda S, Geschwind D H, Freitag C M
Transcriptomic signatures of neuronal differentiation and their
association with risk genes for autism spectrum and related
neuropsychiatric disorders
Translational psychiatry,
2016; 6(8):
e864.
de la Torre-Ubieta Luis, Won Hyejung, Stein Jason L, Geschwind Daniel H
Advancing the understanding of autism disease mechanisms through
genetics
Nature medicine,
2016; 22(4):
345-61.
Smith Imogen, Silveirinha Vasco, Stein Jason L, de la Torre-Ubieta Luis, Farrimond Jonathan A, Williamson Elizabeth M, Whalley Benjamin J
Human neural stem cell-derived cultures in three-dimensional
substrates form spontaneously functional neuronal networks
Journal of tissue engineering and regenerative medicine,
2015;
.
Stein Jason L, de la Torre-Ubieta Luis, Tian Yuan, Parikshak Neelroop N, Hernández Israel A, Marchetto Maria C, Baker Dylan K, Lu Daning, Hinman Cassidy R, Lowe Jennifer K, Wexler Eric M, Muotri Alysson R, Gage Fred H, Kosik Kenneth S, Geschwind Daniel H
A quantitative framework to evaluate modeling of cortical development
by neural stem cells
Neuron,
2014; 83(1):
69-86.
Mejia Luis A, Litterman Nadia, Ikeuchi Yoshiho, de la Torre-Ubieta Luis, Bennett Eric J, Zhang Chi, Harper J Wade, Bonni Azad
A novel Hap1-Tsc1 interaction regulates neuronal mTORC1 signaling and
morphogenesis in the brain
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2013; 33(46):
18015-21.
Ikeuchi Yoshiho, de la Torre-Ubieta Luis, Matsuda Takahiko, Steen Hanno, Okazawa Hitoshi, Bonni Azad
The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling
link that orchestrates ciliary morphogenesis in postmitotic neurons
Cell reports,
2013; 4(5):
879-89.
Salih Dervis A M, Rashid Asim J, Colas Damien, de la Torre-Ubieta Luis, Zhu Ruo P, Morgan Alexander A, Santo Evan E, Ucar Duygu, Devarajan Keerthana, Cole Christina J, Madison Daniel V, Shamloo Mehrdad, Butte Atul J, Bonni Azad, Josselyn Sheena A, Brunet Anne
FoxO6 regulates memory consolidation and synaptic function
Genes & development,
2012; 26(24):
2780-801.
Christensen Ryan, de la Torre-Ubieta Luis, Bonni Azad, Colón-Ramos Daniel A
A conserved PTEN/FOXO pathway regulates neuronal morphology during C.
elegans development
Development (Cambridge, England),
2011; 138(23):
5257-67.
de la Torre-Ubieta Luis, Bonni Azad
Transcriptional regulation of neuronal polarity and morphogenesis in
the mammalian brain
Neuron,
2011; 72(1):
22-40.
Huynh Mai Anh, Ikeuchi Yoshiho, Netherton Stuart, de la Torre-Ubieta Luis, Kanadia Rahul, Stegmüller Judith, Cepko Constance, Bonni Shirin, Bonni Azad
An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal
morphogenesis and positioning in the mammalian brain
Neuron,
2011; 69(5):
930-44.
Bilimoria Parizad M, de la Torre-Ubieta Luis, Ikeuchi Yoshiho, Becker Esther B E, Reiner Orly, Bonni Azad
A JIP3-regulated GSK3β/DCX signaling pathway restricts axon
branching
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2010; 30(50):
16766-76.
de la Torre-Ubieta Luis, Gaudillière Brice, Yang Yue, Ikeuchi Yoshiho, Yamada Tomoko, DiBacco Sara, Stegmüller Judith, Schüller Ulrich, Salih Dervis A, Rowitch David, Brunet Anne, Bonni Azad
A FOXO-Pak1 transcriptional pathway controls neuronal polarity
Genes & development,
2010; 24(8):
799-813.
de la Torre-Ubieta Luis, Bonni Azad
Combinatorial assembly of neurons: from chromatin to dendrites
Trends in cell biology,
2008; 18(2):
48-51.
Iwase Shigeki, Lan Fei, Bayliss Peter, de la Torre-Ubieta Luis, Huarte Maite, Qi Hank H, Whetstine Johnathan R, Bonni Azad, Roberts Thomas M, Shi Yang
The X-linked mental retardation gene SMCX/JARID1C defines a family of
histone H3 lysine 4 demethylases
Cell,
2007; 128(6):
1077-88.
Lasorella Anna, Stegmüller Judith, Guardavaccaro Daniele, Liu Guangchao, Carro Maria S, Rothschild Gerson, de la Torre-Ubieta Luis, Pagano Michele, Bonni Azad, Iavarone Antonio
Degradation of Id2 by the anaphase-promoting complex couples cell
cycle exit and axonal growth
Nature,
2006; 442(7101):
471-4.