Black, Douglas
Titles
Professor, Microbiology, Immunology & Molecular Genetics
Contact Information
Email
dougb@microbio.ucla.edu Phone
Lab Number:
(310) 794-7689
Office Phone Number: (310) 794-7644
Office Phone Number: (310) 794-7644
Address
Laboratory Address:
LaboratoryMRL 6-567
UNITED STATES
Work Address:
OfficeMRL 6-780
CAMPUS - 951489
CA
UNITED STATES
Publications
A selected list of publications:
Damianov Andrey, Ying Yi, Lin Chia-Ho, Lee Ji-Ann, Tran Diana, Vashisht Ajay A, Bahrami-Samani Emad, Xing Yi, Martin Kelsey C, Wohlschlegel James A, Black Douglas L
Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein
Complex LASR
Cell,
2016; 165(3):
606-19.
Vuong Celine K, Black Douglas L, Zheng Sika
The neurogenetics of alternative splicing
Nature reviews. Neuroscience,
2016; 17(5):
265-81.
Linares Anthony J, Lin Chia-Ho, Damianov Andrey, Adams Katrina L, Novitch Bennett G, Black Douglas L
The splicing regulator PTBP1 controls the activity of the
transcription factor Pbx1 during neuronal differentiation
eLife,
2015; 4(1):
e09268.
Sharma Shalini, Wongpalee Somsakul Pop, Vashisht Ajay, Wohlschlegel James A, Black Douglas L
Stem-loop 4 of U1 snRNA is essential for splicing and interacts with
the U2 snRNP-specific SF3A1 protein during spliceosome assembly
Genes & development,
2014; 28(22):
2518-31.
Li Qin, Zheng Sika, Han Areum, Lin Chia-Ho, Stoilov Peter, Fu Xiang-Dong, Black Douglas L
The splicing regulator PTBP2 controls a program of embryonic splicing
required for neuronal maturation
eLife,
2014; 3(22):
e01201.
Zheng Sika, Damoiseaux Robert, Chen Liang, Black Douglas L
A broadly applicable high-throughput screening strategy identifies new
regulators of Dlg4 (Psd-95) alternative splicing
Genome research,
2013; 23(6):
998-1007.
Pandya-Jones Amy, Bhatt Dev M, Lin Chia-Ho, Tong Ann-Jay, Smale Stephen T, Black Douglas L
Splicing kinetics and transcript release from the chromatin
compartment limit the rate of Lipid A-induced gene expression
RNA (New York, N.Y.),
2013; 19(6):
811-27.
Zheng Sika, Gray Erin E, Chawla Geetanjali, Porse Bo Torben, O'Dell Thomas J, Black Douglas L
PSD-95 is post-transcriptionally repressed during early neural
development by PTBP1 and PTBP2
Nature neuroscience,
2012; 15(3):
381-8, S1.
Gehman Lauren T, Meera Pratap, Stoilov Peter, Shiue Lily, O'Brien Janelle E, Meisler Miriam H, Ares Manuel, Otis Thomas S, Black Douglas L
The splicing regulator Rbfox2 is required for both cerebellar
development and mature motor function
Genes & development,
2012; 26(5):
445-60.
Bhatt Dev M, Pandya-Jones Amy, Tong Ann-Jay, Barozzi Iros, Lissner Michelle M, Natoli Gioacchino, Black Douglas L, Smale Stephen T
Transcript dynamics of proinflammatory genes revealed by sequence
analysis of subcellular RNA fractions
Cell,
2012; 150(2):
279-90.
Gehman Lauren T, Stoilov Peter, Maguire Jamie, Damianov Andrey, Lin Chia-Ho, Shiue Lily, Ares Manuel, Mody Istvan, Black Douglas L
The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in
the mammalian brain
Nature genetics,
2011; 43(7):
706-11.
Sharma Shalini, Maris Christophe, Allain Frédéric H-T, Black Douglas L
U1 snRNA directly interacts with polypyrimidine tract-binding protein
during splicing repression
Molecular cell,
2011; 41(5):
579-88.
Lee Ji-Ann, Tang Zhen-Zhi, Black Douglas L
An inducible change in Fox-1/A2BP1 splicing modulates the alternative
splicing of downstream neuronal target exons
Genes & development,
2009; 23(19):
2284-93.
Li, Qin, Lee, Ji-Ann, and Douglas L. Black
Neuronal Regulation of Alternative Pre-messenger RNA Splicing,
Nature Reviews Neuroscience,
2007; 8(11):
819-31.
Boutz P, Stoilov P, Li Q, Lin C, Chawla G, Ostrow K, Shiue L, Manuel C. Ares and Douglas L. Black
Post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons,
Genes and Development,
2007; 21(13):
1636-52.
Underwood J, Boutz P, Dougherty JD, Stoilov P, Black DL
Homologues of the C. Elegans Fox-1 Protein are neuronal splicing regulators in mammals,
MCB,
2005; 25(22):
10005-16.
Black DL
Mechanisms of alternative pre-messenger RNA splicing
Annual review of biochemistry. ,
2003; 72:
291-336.
Xie J, Black DL
A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels
Nature. ,
2001; 410(6831):
936-9.