Biography
Dr. Carrie Bearden received her Ph.D. in Clinical Psychology from the University of Pennsylvania and joined the UCLA faculty as Assistant Professor in the Department of Psychiatry & Biobehavioral Sciences at UCLA in 2003. She hold a secondary appointment in the Department of Psychology. She has received numerous awards and honors, including Young Investigator Awards from the International Congress for Schizophrenia Research and the National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD), and the American College of Neuropsychopharmacology (ACNP), the A.E. Bennett Neuropsychiatric Research Award for Clinical Science in Biological Psychiatry, and the Samuel Gershon Junior Investigator Award from the International Society for Bipolar Disorders. Dr. Bearden's research aims to understand genetic influences on brain structure in the development of psychosis, using converging methods to study cognition and neuroanatomy in clinical high-risk samples (e.g., adolescents at clinical high-risk for psychosis), and in possible 'genetic subtypes of the disease with very high penetrance (e.g, 22q11.2 microdeletions). Another active research project, conducted in collaboration with Dr. Nelson Freimer, is an NIMH-funded study of neural endophenotypes of bipolar disorder in a genetically isolated population in Latin America.
Publications
A selected list of publications:
Delio Maria, Guo Tingwei, McDonald-McGinn Donna M, Zackai Elaine, Herman Sean, Kaminetzky Mark, Higgins Anne Marie, Coleman Karlene, Chow Carolyn, Jarlbrzkowski Maria, Bearden Carrie E, Bailey Alice, Vangkilde Anders, Olsen Line, Olesen Charlotte, Skovby Flemming, Werge Thomas M, Templin Ludivine, Busa Tiffany, Philip Nicole, Swillen Ann, Vermeesch Joris R, Devriendt Koen, Schneider Maude, Dahoun Sophie, Eliez Stephan, Schoch Kelly, Hooper Stephen R, Shashi Vandana, Samanich Joy, Marion Robert, van Amelsvoort Therese, Boot Erik, Klaassen Petra, Duijff Sasja N, Vorstman Jacob, Yuen Tracy, Silversides Candice, Chow Eva, Bassett Anne, Frisch Amos, Weizman Abraham, Gothelf Doron, Niarchou Maria, van den Bree Marianne, Owen Michael J, Suñer Damian Heine, Andreo Jordi Rosell, Armando Marco, Vicari Stefano, Digilio Maria Cristina, Auton Adam, Kates Wendy R, Wang Tao, Shprintzen Robert J, Emanuel Beverly S, Morrow Bernice E
Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial
and DiGeorge syndromes
American journal of human genetics,
2013; 92(3):
439-47.
Foland-Ross Lara C, Thompson Paul M, Sugar Catherine A, Narr Katherine L, Penfold Conor, Vasquez Roxanne E, Townsend Jennifer, Fischer Jeffrey, Saharan Priya, Bearden Carrie E, Altshuler Lori L
Three-dimensional mapping of hippocampal and amygdalar structure in
euthymic adults with bipolar disorder not treated with lithium
Psychiatry research,
2013; 211(3):
195-201.
Gee Dylan G, Karlsgodt Katherine H, van Erp Theo G M, Bearden Carrie E, Lieberman Matthew D, Belger Aysenil, Perkins Diana O, Olvet Doreen M, Cornblatt Barbara A, Constable Todd, Woods Scott W, Addington Jean, Cadenhead Kristin S, McGlashan Thomas H, Seidman Larry J, Tsuang Ming T, Walker Elaine F, Cannon Tyrone D, Cannon Tyrone D
Altered age-related trajectories of amygdala-prefrontal circuitry in
adolescents at clinical high risk for psychosis: a preliminary study
Schizophrenia research,
2012; 134(1):
1-9.
Ho Jennifer S, Radoeva Petya D, Jalbrzikowski Maria, Chow Carolyn, Hopkins Jessica, Tran Wen-Ching, Mehta Ami, Enrique Nicole, Gilbert Chelsea, Antshel Kevin M, Fremont Wanda, Kates Wendy R, Bearden Carrie E
Deficits in mental state attributions in individuals with 22q11.2
deletion syndrome (velo-cardio-facial syndrome)
Autism research : official journal of the International Society for Autism Research,
2012; 5(6):
407-18.
van Erp Theo G M, Thompson Paul M, Kieseppä Tuula, Bearden Carrie E, Marino Alexandria C, Hoftman Gil D, Haukka Jari, Partonen Timo, Huttunen Matti, Kaprio Jaakko, Lönnqvist Jouko, Poutanen Veli-Pekka, Toga Arthur W, Cannon Tyrone D
Hippocampal morphology in lithium and non-lithium-treated bipolar I
disorder patients, non-bipolar co-twins, and control twins
Human brain mapping,
2012; 33(3):
501-10.
Acosta Maria T, Bearden Carrie E, Castellanos F Xavier, Castellanos Xavier F, Cutting Laurie, Elgersma Ype, Gioia Gerard, Gutmann David H, Lee Yong-Seok, Legius Eric, Muenke Maximillian, North Kathryn, Parada Luis F, Ratner Nancy, Hunter-Schaedle Kim, Silva Alcino J
The Learning Disabilities Network (LeaDNet): using neurofibromatosis
type 1 (NF1) as a paradigm for translational research
American journal of medical genetics. Part A,
2012; 158A(9):
2225-32.
Bearden Carrie E, van Erp Theo G M, Dutton Rebecca A, Boyle Christina, Madsen Sarah, Luders Eileen, Kieseppa Tuula, Tuulio-Henriksson Annamari, Huttunen Matti, Partonen Timo, Kaprio Jaakko, Lönnqvist Jouko, Thompson Paul M, Cannon Tyrone D
Mapping corpus callosum morphology in twin pairs discordant for
bipolar disorder
Cerebral cortex (New York, N.Y. : 1991),
2011; 21(10):
2415-24.
Green Michael F, Bearden Carrie E, Cannon Tyrone D, Fiske Alan P, Hellemann Gerhard S, Horan William P, Kee Kimmy, Kern Robert S, Lee Junghee, Sergi Mark J, Subotnik Kenneth L, Sugar Catherine A, Ventura Joseph, Yee Cindy M, Nuechterlein Keith H
Social Cognition in Schizophrenia, Part 1: Performance Across Phase of
Illness
Schizophrenia bulletin,
2011; 69(10):
.
Bearden Carrie E, Shih Vivian H, Green Michael F, Gitlin Michael, Sokolski Kenneth N, Levander Eric, Marusak Susan, Hammen Constance, Sugar Catherine A, Altshuler Lori L
The impact of neurocognitive impairment on occupational recovery of
clinically stable patients with bipolar disorder: a prospective study
Bipolar disorders,
2011; 13(4):
323-33.
Yee Cindy M, Mathis Kristopher Ian, Sun Jane C, Sholty Gretchen L, Lang Peter J, Bachman Peter, Williams Terrance J, Bearden Carrie E, Cannon Tyrone D, Green Michael F, Subotnik Kenneth L, Ventura Joseph, Nuechterlein Keith H
Integrity of emotional and motivational states during the prodromal,
first-episode, and chronic phases of schizophrenia
Journal of abnormal psychology,
2010; 119(1):
71-82.
Shilyansky Carrie, Karlsgodt Katherine H, Cummings Damian M, Sidiropoulou Kyriaki, Hardt Molly, James Alex S, Ehninger Dan, Bearden Carrie E, Poirazi Panayiota, Jentsch J David, Cannon Tyrone D, Levine Michael S, Silva Alcino J
Neurofibromin regulates corticostriatal inhibitory networks during
working memory performance
Proceedings of the National Academy of Sciences of the United States of America,
2010; 107(29):
13141-6.
Seidman Larry J, Giuliano Anthony J, Meyer Eric C, Addington Jean, Cadenhead Kristin S, Cannon Tyrone D, McGlashan Thomas H, Perkins Diana O, Tsuang Ming T, Walker Elaine F, Woods Scott W, Bearden Carrie E, Christensen Bruce K, Hawkins Keith, Heaton Robert, Keefe Richard S E, Heinssen Robert, Cornblatt Barbara A, Cornblatt Barbara A
Neuropsychology of the prodrome to psychosis in the NAPLS consortium:
relationship to family history and conversion to psychosis
Archives of general psychiatry,
2010; 67(6):
578-88.
Yatham Lakshmi N, Torres Ivan J, Malhi Gin S, Frangou Sophia, Glahn David C, Bearden Carrie E, Burdick Katherine E, MartÃnez-Arán Anabel, Dittmann Sandra, Goldberg Joseph F, Ozerdem Aysegul, Aydemir Omer, Chengappa K N Roy
The International Society for Bipolar Disorders-Battery for Assessment
of Neurocognition (ISBD-BANC)
Bipolar disorders,
2010; 12(4):
351-63.
Bearden Carrie E, van Erp Theo G M, Dutton Rebecca A, Lee Agatha D, Simon Tony J, Cannon Tyrone D, Emanuel Beverly S, McDonald-McGinn Donna, Zackai Elaine H, Thompson Paul M
Alterations in midline cortical thickness and gyrification patterns
mapped in children with 22q11.2 deletions
Cerebral cortex (New York, N.Y. : 1991),
2009; 19(1):
115-26.
Sun Daqiang, van Erp Theo G M, Thompson Paul M, Bearden Carrie E, Daley Melita, Kushan Leila, Hardt Molly E, Nuechterlein Keith H, Toga Arthur W, Cannon Tyrone D
Elucidating a magnetic resonance imaging-based neuroanatomic biomarker
for psychosis: classification analysis using probabilistic brain atlas
and machine learning algorithms
Biological psychiatry,
2009; 66(11):
1055-60.
Torrey E Fuller, Buka Stephen, Cannon Tyrone D, Goldstein Jill M, Seidman Larry J, Liu Tianli, Hadley Trevor, Rosso Isabelle M, Bearden Carrie, Yolken Robert H
Paternal age as a risk factor for schizophrenia: how important is it?
Schizophrenia research,
2009; 114(1-3):
1-5.
van Erp Theo G M, Lesh Tyler A, Knowlton Barbara J, Bearden Carrie E, Hardt Molly, Karlsgodt Katherine H, Shirinyan David, Rao Vikas, Green Michael F, Subotnik Kenneth L, Nuechterlein Keith, Cannon Tyrone D
Remember and know judgments during recognition in chronic
schizophrenia
Schizophrenia research,
2008; 100(1-3):
181-90.
Bearden Carrie E, Soares Jair C, Klunder Andrea D, Nicoletti Mark, Dierschke Nicole, Hayashi Kiralee M, Narr Katherine L, Brambilla Paolo, Sassi Roberto B, Axelson David, Ryan Neal, Birmaher Boris, Thompson Paul M
Three-dimensional mapping of hippocampal anatomy in adolescents with
bipolar disorder
Journal of the American Academy of Child and Adolescent Psychiatry,
2008; 47(5):
515-25.
Bearden Carrie E, Thompson Paul M, Dutton Rebecca A, Frey Benício N, Peluso Marco A M, Nicoletti Mark, Dierschke Nicole, Hayashi Kiralee M, Klunder Andrea D, Glahn David C, Brambilla Paolo, Sassi Roberto B, Mallinger Alan G, Soares Jair C
Three-dimensional mapping of hippocampal anatomy in unmedicated and
lithium-treated patients with bipolar disorder
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
2008; 33(6):
1229-38.
Bearden Carrie E, Thompson Paul M, Dalwani Manish, Hayashi Kiralee M, Lee Agatha D, Nicoletti Mark, Trakhtenbroit Michael, Glahn David C, Brambilla Paolo, Sassi Roberto B, Mallinger Alan G, Frank Ellen, Kupfer David J, Soares Jair C
Greater cortical gray matter density in lithium-treated patients with
bipolar disorder
Biological psychiatry,
2007; 62(1):
7-16.
Bearden Carrie E, van Erp Theo G M, Dutton Rebecca A, Tran Helen, Zimmermann Lara, Sun Daqiang, Geaga Jennifer A, Simon Tony J, Glahn David C, Cannon Tyrone D, Emanuel Beverly S, Toga Arthur W, Thompson Paul M
Mapping cortical thickness in children with 22q11.2 deletions
Cerebral cortex (New York, N.Y. : 1991),
2007; 17(8):
1889-98.
Bearden Carrie E, Glahn David C, Monkul E Serap, Barrett Jennifer, Najt Pablo, Kaur Simerjit, Sanches Marsal, Villarreal Veronica, Bowden Charles, Soares Jair C
Sources of declarative memory impairment in bipolar disorder: mnemonic
processes and clinical features
Journal of psychiatric research,
2006; 40(1):
47-58.
Simon Tony J, Bish Joel P, Bearden Carrie E, Ding Lijun, Ferrante Samantha, Nguyen Vy, Gee James C, McDonald-McGinn Donna M, Zackai Elaine H, Emanuel Beverly S
A multilevel analysis of cognitive dysfunction and psychopathology
associated with chromosome 22q11.2 deletion syndrome in children
Development and psychopathology,
2005; 17(3):
753-84.
Bearden Carrie E, Jawad Abbas F, Lynch David R, Monterossso John R, Sokol Set, McDonald-McGinn Donna M, Saitta Sulagna C, Harris Stacy E, Moss Edward, Wang Paul P, Zackai Elaine, Emanuel Beverly S, Simon Tony J
Effects of COMT genotype on behavioral symptomatology in the 22q11.2
Deletion Syndrome
Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence,
2005; 11(1):
109-17.
Meyer Stephanie E, Bearden Carrie E, Lux Sabrina R, Gordon Jamie L, Johnson Jennifer K, O'Brien Mary P, Niendam Tara A, Loewy Rachel L, Ventura Joseph, Cannon Tyrone D
The psychosis prodrome in adolescent patients viewed through the lens
of DSM-IV
Journal of child and adolescent psychopharmacology,
2005; 15(3):
434-51.
Bearden Carrie E, Jawad Abbas F, Lynch David R, Sokol Set, Kanes Steven J, McDonald-McGinn Donna M, Saitta Sulagna C, Harris Stacy E, Moss Edward, Wang Paul P, Zackai Elaine, Emanuel Beverly S, Simon Tony J
Effects of a functional COMT polymorphism on prefrontal cognitive
function in patients with 22q11.2 deletion syndrome
The American journal of psychiatry,
2004; 161(9):
1700-2.
Bearden Carrie E, van Erp Theo G M, Monterosso John R, Simon Tony J, Glahn David C, Saleh Peter A, Hill Nicole M, McDonald-McGinn Donna M, Zackai Elaine, Emanuel Beverly S, Cannon Tyrone D
Regional brain abnormalities in 22q11.2 deletion syndrome: association
with cognitive abilities and behavioral symptoms
Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology,
2004; 10(3):
198-206.
Cannon Tyrone D, van Erp Theo G M, Bearden Carrie E, Loewy Rachel, Thompson Paul, Toga Arthur W, Huttunen Matti O, Keshavan Matcheri S, Seidman Larry J, Tsuang Ming T
Early and late neurodevelopmental influences in the prodrome to
schizophrenia: contributions of genes, environment, and their
interactions
Schizophrenia bulletin,
2003; 29(4):
653-69.