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What
characterizes the educational program of the
IDP?
The goal of the program is to train students to be conversant in
all levels of analysis in neuroscience, from the molecular and
cellular to systems, behavior, translation, and disease, while specializing in their chosen field
of research.
How
large is
the
Program?
Currently, the IDP comprises 85 doctoral students.
On
average, 15 new students enter the program every year.
Who
are the faculty in the
IDP?
All UCLA faculty with an active research program in neuroscience can
be members of the IDP. The faculty belong to many
departments in the School of Medicine, College of Letters &
Sciences, School of Engineering, School of Nursing and School of
Dentistry.
For details on individual faculty click here.
What
areas of neuroscience are represented in the
IDP?
The
IDP
has great
breadth and includes distinguished faculty in many areas of neuroscience.
Several areas are represented by large groups of faculty with common interests
who closely interact with each other in a collaborative manner. A number of
these clusters of faculty are represented as an area of specialty within the IDP which we call a Focused Area of Research (FAR). The FARs presently
available in the IDP are Addiction; Learning & Memory; Neural Development, Degeneration &
Repair; Neurogenetics; Neuroimaging/Cognitive; and Synapses, Cells
& Circuits. The curricula for each FAR are generally similar and consist of two or more
courses and at least two journal clubs.
The following is a brief description of each of the current FARs:
Addiction

UCLA is internationally recognized for
excellence in Addiction research, which represents a multidisciplinary
and translational area of neuroscience research at UCLA. Research spans
the fundamental bases of addiction from the genome to neural phenotypes
and ultimately the syndrome. Ongoing programs focus on a variety of
addictive disorders that include drug abuse (psychostimulants, opioids,
alcohol and nicotine) and other addictions, and are supported within
several NIH funded centers and training programs. The programs are
particularly strong in molecular and cellular neurobiology, brain imaging, and
behavioral neuroscience. Students in the Addiction FAR will join a highly
interactive community where they will have the opportunity to participate in a
number of seminars and courses.
Learning and Memory

The goal
of learning and memory research is to understand how we allocate,
acquire, retain, and retrieve information. By its very nature, this
research is integrative and cross-disciplinary, incorporating molecular, cell biological, systems and behavioral level approaches to study
synapses, neurons, circuits, brains and behavior. UCLA is
internationally recognized for the excellence of its research in
learning and memory. Together, its outstanding faculty cover molecular
to systems approaches to the study of memory, working in model systems
ranging from Aplysia to mouse to humans. Students in the Learning and
Memory FAR will become part of this interactive and energetic community
with organized, well-attended scientific activities, including a
long-standing weekly Learning and Memory Journal Club, an annual
Southern California Learning and Memory Symposium, and a myriad of other
events that highlight the strengths of this community. Additional new courses are being developed
to further enrich the training opportunities.
Neural Development,
Degeneration, and Repair

Neurological diseases and injuries are among the most debilitating
medical conditions affecting millions of people each year. Few effective
treatments for these disorders currently exist, in part because we know
very little about the mechanisms underlying these conditions and how to
prevent or repair neural damage. The Neural Development, Degeneration,
and Repair FAR seeks to tackle this problem by providing training in
three main areas: 1) Elucidating the cellular and molecular mechanisms
that establish neural circuitry during embryonic and postnatal
development, 2) Exploring mechanisms of aging and neurodegeneration
caused by injury or diseases, and 3) Exploring ways in which neural tissue
damage can be prevented or repaired. The Neural Development, Degeneration, and
Repair FAR will draw upon the broad expertise at UCLA in the areas of stem cell
differentiation, neural development, neurodegenerative diseases, plasticity and
restoration of function after injury to the central nervous system. The faculty
associated with the FAR includes basic and clinical scientists, many of whom
bridge the gap between the laboratory and advances in therapies for
neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s,
as well as brain and spinal cord injuries. The Neural Development, Degeneration,
and Repair FAR curriculum includes training in broad areas of cellular,
molecular and system neuroscience, completed with specialized courses in Neural
Development, Degeneration, and Repair, a weekly journal club focused on the
current literature, weekly presentations by trainees and faculty, and seminars
from renowned investigators in the field. Students
are encouraged to explore areas at the junction of multiple fields, to
use multiple technical approaches, and to engage in collaborations
between laboratories. The Neural Development, Degeneration, and Repair
FAR also will build upon the success of their NIH-sponsored Training
Program in Neural Repair. The goal is to train a cadre of young
investigators that are fully prepared for the changing culture of
science while retaining a solid background in their main area of
expertise.
Neurogenetics

Neurogenetics brings to bear the powerful tools of modern genetics and
genomics to some of the most important and fascinating problems in all
of biomedical sciences. UCLA is widely recognized as one of the leading
centers of neurogenetics research. The breadth of the neurogenetics research program is extraordinary, ranging from
investigations of invertebrate model systems within single laboratories
to trans-disciplinary collaborative programs focused on complex human
phenotypes, in the Consortium for Neuropsychiatric Phenomics. The
Neurogenetics FAR is built around a well-established training structure
and NIH-funded joint predoctoral and postdoctoral training programs in
Neurobehavioral Genetics. These training programs exemplify the
signature focus of the FAR; using genetics to integrate “neuro” and
“behavioral” approaches to neuroscience investigation, with a particular
emphasis on phenotyping of the nervous system-across systems from flies
to humans-as a distinct scientific endeavor. Current faculty within the
NIH-funded training programs represent a wide diversity of research
interests and provide a broad range of opportunities for students. There
is already an enormous level of interaction between faculty in the
program, and this is enhanced by a yearly retreat, bi-monthly seminar
series and a flexible core curriculum tailored to individual student
backgrounds.
Neuroimaging/Cognitive

The
Neuroimaging/Cognitive FAR
is designed for students pursuing a professional career in neuroimaging, either
in clinical practice or in neuroscience research. The multidisciplinary
approach provides training in both basic science and technological
principles of modern neuroimaging methods, and in their application to
the understanding of neurological function and neurological disorders.
The Neuroimaging/Cognitive FAR is comprised of a set of selected core and elective
courses designed to provide students with a firm grounding in the
theoretical, conceptual, and practical issues involved in studying the
human and non-human brain using neuroimaging methods - from the
molecular to whole brain human imaging. Core courses allow students
to gain an understanding of the physiological principles underlying the
types of imaging modalities commonly used to examine micro- and macro-
brain structure and function as well as psychologically induced changes
in physiological signals. The FAR includes research design and data
analysis. Participants will obtain hands-on experience with data
acquisition, processing, statistical analysis, and visualization through
the use of leading edge graphical workflow environments and image
processing software packages. Core courses emphasize the consideration
of brain structure and function using modern medical imaging (e.g. MRI,
PET, OIS, etc) and related neural recording techniques (e.g. EEG).
Across these intensive courses, students will gain a full appreciation
of the various cognitive factors that influence patterns of brain
activation measured with functional imaging methods (e.g. BOLD, fMRI and
PET) as well as becoming familiar with the effects of disease on brain
anatomy and integrity. Students will gain
exposure to neural tissue imaging methods (e.g. light, confocal,
molecular, and related microscopy approaches), their application,
and comparative strengths and limitations. At the completion of the Neuroimaging FAR, it is expected that participants will be fully
prepared to critique, design, and participate in conducting research
studies using a variety of neuroimaging methods; appreciate potentials
and limitations of current neuroimaging methods and techniques; better
understand the broad range of expertise required in a brain imaging
research program; and be positioned well for careers in neuroimaging
laboratory research.
Synapses, Cells, and
Circuits

The
Synapses, Cells, and
Circuits FAR focuses on how the nervous system works by
linking physiological mechanisms at the synaptic, cellular and circuit
levels. Ultimately these efforts seek to understand in detail how
synaptic function and plasticity, properties intrinsic to individual
neurons, and microcircuit function converge to process information in
different brain areas. Over the past decades neuroscience has elucidated
basic principles underlying neuronal excitability and synaptic function.
There also is increasingly accurate specification of the brain regions
involved in particular behaviors through neuroimaging. However, due to
technical challenges, relatively little research links these critical
physiological levels. Bridging this gap will require the next generation
of scientists to have expertise in neuronal cell biology, synaptic
physiology, genetic approaches, and modern optical techniques. Given the
breadth of neuroscience expertise at UCLA, this FAR is ideally positioned to
lead research and training in this field.
Where can I find more details
and apply to the
IDP?
Please
visit the pages for our
program curriculum and
admission
procedures.
Additional
Faculty Information
Please note that some investigators conduct research that span several
areas and that many faculty are not listed in the affinity clusters below
because they work in other areas of neuroscience. Please consult the
alphabetical listing
for more details and a complete list of IDP faculty.
Brain
Imaging
Bearden, Carrie
Bilder, Robert
Bookheimer, Susan
Cohen, Mark
Dapretto, Mirella
Engel, Jerome
Harper, Ronald
Harris,
Neil
Hovda, David
Iacoboni, Marco
Kornblum, Harley
Liu, Zili
London, Edythe
Mayer, Emeran
Mazziotta, John
McCracken, James
Thompson,
Paul
Toga, Arthur
Zaidel, Eran
Developmental
Neuroscience
Arnold, Arthur
Bronstein, Jeff
Carpenter, Ellen
Chesselet, Marie-Françoise
de Vellis, Jean
Fan, Guoping
Faull, Kym
Fisher, Robin
Geschwind, Daniel
Gomez-Pinilla, Fernando
,
Hartenstein, Volker
Houser, Carolyn
Hovda, David
Kaufman, Daniel
Kornblum, Harley
Levine, Michael
McCracken, James
Novitch, Bennett
Phelps, Patricia
Portera-Cailliau,
Carlos
Sagasti, Alvaro
Spigelman, Igor
Vilain, Eric
Waschek, James
Yang, Xian-Jie
Zipursky, Larry
Learning
and Memory
Blaisdell, Aaron
Buonomano, Dean
Colwell, Christopher
Engel, Jerome
Fanselow, Michael
Faull, Kym
Fried, Itzhak
Glanzman, David
Knowlton, Barbara
Krasne, Franklin
Liu, Zili
Martin, Kelsey
Mazziotta, John
Mody, Istvan
O'Dell, Thomas
Otis, Tom
Portera-Cailliau,
Carlos
Schweizer, Felix
Silva, Alcino
Smith, Desmond
White, Stephanie
Xie, Cui-Wei (Tracy)
Neural
Degeneration
and
Repair
Bronstein, Jeff
Carmichael, S. Thomas
Chesselet, Marie-Françoise
de Vellis, Jean
Edgerton, V. Reggie
Engel, Jerome
Fan, Guoping
Faull, Kym
Geschwind, Daniel
Gomez-Pinilla, Fernando
Guo, Ming
Guo, Zhefeng
Gylys, Karen
Harris,
Neil
Hovda, David
Kagan, Bruce
Kaufman, Daniel
Kornblum, Harley
Levine, Michael
Liau, Linda
Maidment, Nigel
Mischel, Paul
Mody, Istvan
Novitch, Bennett
Phelps, Patricia
Portera-Cailliau,
Carlos
Siegel, Jerome
Sofroniew, Michael
Spigelman, Igor
Sun, Yi
Teplow, David
Voskuhl, Rhonda
Waschek, James
Yang, X. William
Neuroendocrinology
Arnold, Arthur
Faull, Kym
Mayer, Emeran
Micevych, Paul
Schlinger, Barney
Stefani, Enrico
Vilain, Eric
Waschek, James
Wayne, Nancy
White, Stephanie
Neuroengineering
Arnold, Arthur
Bookheimer, Susan
Buonomano, Dean
Cohen, Mark
Edgerton, V. Reggie
Feldman, Jack
Frye,
Mark
Levine, Michael
Maidment, Nigel
Mazziotta, John
Mody, Istvan
Narins, Peter
Otis, Tom
Ringach, Dario
Smith, Desmond
Sofroniew, Michael
Thompson,
Paul
Toga, Arthur
Neurogenetics
and Pharmacogenetics
Arnold, Arthur
Bearden, Carrie
Bilder, Robert
Fan, Guoping
Freimer, Nelson
Geschwind, Daniel
,
McCracken, James
Ray, Lara
Siegel, Jerome
Vilain, Eric
Yang, X. William
Small
Systems, Synaptic Physiology,
Channel Biophysics and Receptors
Brecha, Nicholas
Chandler, Scott
Colwell, Christopher
Engel, Jerome
Evans, Christopher
Fain, Gordon
Feldman, Jack
Glanzman, David
Gundersen, Cameron
Kagan, Bruce
Krantz, David
Krasne, Franklin
Levine, Michael
London, Edythe
Maidment, Nigel
Micevych, Paul
Mody, Istvan
Narins, Peter
O'Dell, Thomas
Olcese, Riccardo
Otis, Tom
Papazian, Diane
Ringach, Dario
Schweizer, Felix
Silva, Alcino
Spigelman, Igor
Stefani, Enrico
Wayne, Nancy
White, Stephanie
Xie, Cui-Wei (Tracy)

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