Brain Research Institute
Neuroscience GPB Home Area
Work Phone Number: 310-206-2189
Office Address:300 Stein Plaza Suite 562
Los Angeles, CA 90095
BiographyMy laboratory focuses on using advanced brain mapping techniques to develop restorative neurosurgical interventions and to identify imaging biomarkers to monitor such interventions. Specific areas of research include: 1) Design of a population-based Parkinson?s Disease atlas to investigate morphological changes associated with this disease and possible targets for restorative therapies. 2) Developing and testing fMRI algorithms to individualize restorative interventions, such as fMRI maps to target Deep Brain Stimulation electrode placement 3) Mapping the functional reorganization of the brain after stroke to identify network level changes that are predictive of compensation and recovery and that can be targeted to enhance recovery 4) EEG and ECoG based brain-computer interface and real-time intraoperative mapping
A selected list of publications:
Tsiokos Christos, Hu Xiao, Pouratian Nader 200-300Hz movement modulated oscillations in the internal globus pallidus of patients with Parkinson's Disease Neurobiology of disease, 2013; 54: 464-74.
Garrett Matthew C, Bilgin-Freiert Arzu, Bartels Christine, Everson Richard, Afsarmanesh Nasim, Pouratian Nader An Evidence-Based Approach to the Efficient Use of CT-imaging in the Neurosurgical Patient Neurosurgery, 2013; 54: .
Zheng Zhong, Shemmassian Shirag, Wijekoon Christopher, Kim Won, Bookheimer Susan Y, Pouratian Nader DTI correlates of distinct cognitive impairments in Parkinson's disease Human brain mapping, 2013; 54: .
Speier William, Fried Itzhak, Pouratian Nader Improved P300 speller performance using electrocorticography, spectral features, and natural language processing Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2013; 54: .
Lu Jessica, Speier William, Hu Xiao, Pouratian Nader The effects of stimulus timing features on P300 speller performance Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2013; 124(2): 306-14.
Bari Ausaf A, Pouratian Nader Brain imaging correlates of peripheral nerve stimulation Surgical neurology international, 2012; 3(Suppl 4): S260-8.
Kim Won, Clelland Claire, Yang Isaac, Pouratian Nader Comprehensive review of stereotactic radiosurgery for medically and surgically refractory pituitary adenomas Surgical neurology international, 2012; 3(Suppl 2): S79-89.
Sheehan Jason, Starke Robert M, Pouratian Nader, Litvack Zachary, Asthagiri Ashok Identification of Knowledge Gaps in Neurosurgery Through Analysis of Responses to the Self-Assessment in Neurological Surgery (SANS) World neurosurgery, 2012; 215(6): .
Sheehan Jason, Starke Robert M, Pouratian Nader, Litvack Zachary Identification of Knowledge Gaps in Neurosurgery Using a Validated Self-Assessment Examination: Differences Between General and Spinal Neurosurgeons World neurosurgery, 2012; 215(6): .
Speier William, Arnold Corey, Lu Jessica, Taira Ricky K, Pouratian Nader Natural language processing with dynamic classification improves P300 speller accuracy and bit rate Journal of neural engineering, 2012; 9(1): 016004.
Garrett Matthew, Pouratian Nader Repeat head CT scan in blunt trauma patients Journal of the American College of Surgeons, 2012; 215(6): 897; author reply 898.
Garrett Matthew C, Pouratian Nader, Liau Linda M Use of language mapping to aid in resection of gliomas in eloquent brain regions Neurosurgery clinics of North America, 2012; 23(3): 497-506.
Elias W Jeffrey, Zheng Zhong A, Domer Paul, Quigg Mark, Pouratian Nader Validation of connectivity-based thalamic segmentation with direct electrophysiologic recordings from human sensory thalamus NeuroImage, 2012; 59(3): 2025-34.
Pouratian Nader, Reames Davis L, Frysinger Robert, Elias W Jeff Comprehensive analysis of risk factors for seizures after deep brain stimulation surgery. Clinical article Journal of neurosurgery, 2011; 115(2): 310-5.
Sedrak Mark, Gorgulho Alessandra, Frew Andrew, Behnke Eric, DeSalles Antonio, Pouratian Nader Diffusion tensor imaging and colored fractional anisotropy mapping of the ventralis intermedius nucleus of the thalamus Neurosurgery, 2011; 69(5): 1124-9; discussion 1129-30.
Sheehan Jason P, Pouratian Nader, Steiner Ladislau, Laws Edward R, Vance Mary Lee Gamma Knife surgery for pituitary adenomas: factors related to radiological and endocrine outcomes Journal of neurosurgery, 2011; 114(2): 303-9.
Sherman Jonathan H, Moldovan Krisztina, Yeoh H Kwang, Starke Robert M, Pouratian Nader, Shaffrey Mark E, Schiff David Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas Journal of neurosurgery, 2011; 114(6): 1617-21.
Pouratian Nader, Zheng Zhong, Bari Ausaf A, Behnke Eric, Elias W Jeff, Desalles Antonio A F Multi-institutional evaluation of deep brain stimulation targeting using probabilistic connectivity-based thalamic segmentation Journal of neurosurgery, 2011; 115(5): 995-1004.
Chou Arthur P, Lalezari Shadi, Fong Brendan M, Dye Justin, Pham Tracie, Vinters Harry V, Pouratian Nader Post-transplantation primary central nervous system lymphoma: A case report and review of the literature Surgical neurology international, 2011; 2(2): 130.
Kiehna Erin N, Starke Robert M, Pouratian Nader, Dumont Aaron S Standards for reporting randomized controlled trials in neurosurgery Journal of neurosurgery, 2011; 114(2): 280-5.
Soleymani Teo, Pieton David, Pezeshkian Patrick, Miller Patrick, Gorgulho Alessandra A, Pouratian Nader, De Salles Antonio A F Surgical approaches to tinnitus treatment: A review and novel approaches Surgical neurology international, 2011; 2(2): 154.
Pouratian Nader The brain and computer: The neurosurgical interface Surgical neurology international, 2011; 2(2): 79.
Medel Ricky, Pouratian Nader, Elias W Jeffrey Catheter-tip mass mimicking a spinal epidural hematoma Journal of neurosurgery. Spine, 2010; 12(1): 66-71.
Sedrak Mark, Gorgulho Alessandra, Bari Ausaf, Behnke Eric, Frew Andrew, Gevorkyan Inga, Pouratian Nader, DeSalles Antonio Diffusion tensor imaging (DTI) and colored fractional anisotropy (FA) mapping of the subthalamic nucleus (STN) and the globus pallidus interna (GPi) Acta neurochirurgica, 2010; 152(12): 2079-84.
Pouratian Nader, Elias W Jeff, Jane John A, Phillips Lawrence H, Jane John A Electrophysiologically guided untethering of secondary tethered spinal cord syndrome Neurosurgical focus, 2010; 29(1): E3.
Lee Darrin J, Pouratian Nader, Bookheimer Susan Y, Martin Neil A Factors predicting language lateralization in patients with perisylvian vascular malformations. Clinical article Journal of neurosurgery, 2010; 113(4): 723-30.
Sherman Jonathan H, Prevedello Daniel M, Shah Lubdha, Raghavan Prashant, Pouratian Nader, Starke Robert M, Lopes M Beatriz S, Shaffrey Mark E, Schiff David MR imaging characteristics of oligodendroglial tumors with assessment of 1p/19q deletion status Acta neurochirurgica, 2010; 152(11): 1827-34.
Pouratian Nader, Schiff David Management of low-grade glioma Current neurology and neuroscience reports, 2010; 10(3): 224-31.
Pouratian Nader, Bookheimer Susan Y The reliability of neuroanatomy as a predictor of eloquence: a review Neurosurgical focus, 2010; 28(2): E3.
Pouratian Nader, Crowley R Webster, Sherman Jonathan H, Jagannathan Jay, Sheehan Jason P Gamma Knife radiosurgery after radiation therapy as an adjunctive treatment for glioblastoma Journal of neuro-oncology, 2009; 94(3): 409-18.
Jagannathan Jay, Yen Chun-Po, Ray Dibyendu Kumar, Schlesinger David, Oskouian Rod J, Pouratian Nader, Shaffrey Mark E, Larner James, Sheehan Jason P Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases Journal of neurosurgery, 2009; 111(3): 431-8.
Jagannathan Jay, Vates G Edward, Pouratian Nader, Sheehan Jason P, Patrie James, Grady M Sean, Jane John A Impact of the Accreditation Council for Graduate Medical Education work-hour regulations on neurosurgical resident education and productivity Journal of neurosurgery, 2009; 110(5): 820-7.
Jagannathan Jay, Yen Chun-Po, Pouratian Nader, Laws Edward R, Sheehan Jason P Stereotactic radiosurgery for pituitary adenomas: a comprehensive review of indications, techniques and long-term results using the Gamma Knife Journal of neuro-oncology, 2009; 92(3): 345-56.
Sheehan Jason, Pouratian Nader Stereotactic radiosurgery: quo vadis? Neurosurgical focus, 2009; 27(6): E1.
Pouratian Nader, Mut Melike, Jagannathan Jay, Lopes M Beatriz, Shaffrey Mark E, Schiff David Low-grade gliomas in older patients: a retrospective analysis of prognostic factors Journal of neuro-oncology, 2008; 90(3): 341-50.
Prevedello Daniel M, Pouratian Nader, Sherman Jonathan, Jane John A, Vance Mary Lee, Lopes M Beatriz, Laws Edward R Management of Cushing's disease: outcome in patients with microadenoma detected on pituitary magnetic resonance imaging Journal of neurosurgery, 2008; 109(4): 751-9.
Neyns Bart, Cordera Susanna, Joosens Eric, Pouratian Nader, Nader Pouratian Non-Hodgkin's lymphoma in patients with glioma treated with temozolomide Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008; 26(27): 4518-9.
Sherman Jonathan H, Pouratian Nader, Okonkwo David O, Jane John A, Laws Edward R Reconstruction of the sellar dura in transsphenoidal surgery using an expanded polytetrafluoroethylene dural substitute Surgical neurology, 2008; 69(1): 73-6; discussion 76.
Sheehan Jason, Ionescu Adina, Pouratian Nader, Hamilton D Kojo, Schlesinger David, Oskouian Rod J, Sansur Charles Use of trans sodium crocetinate for sensitizing glioblastoma multiforme to radiation: laboratory investigation Journal of neurosurgery, 2008; 108(5): 972-8.
Asthagiri Ashok R, Pouratian Nader, Sherman Jonathan, Ahmed Galal, Shaffrey Mark E Advances in brain tumor surgery Neurologic clinics, 2007; 25(4): 975-1003, viii-ix.
Pouratian Nader, Sansur Charles A, Newman Steven A, Jane John A, Jane John A Chiari malformations in patients with uncorrected sagittal synostosis Surgical neurology, 2007; 67(4): 422-7; discussion 427-8.
Jagannathan Jay, Sheehan Jason P, Pouratian Nader, Laws Edward R, Steiner Ladislau, Vance Mary Lee Gamma Knife surgery for Cushing's disease Journal of neurosurgery, 2007; 106(6): 980-7.
Sansur Charles A, Frysinger Robert C, Pouratian Nader, Fu Kai-Ming, Bittl Markus, Oskouian Rod J, Laws Edward R, Elias W Jeffrey Incidence of symptomatic hemorrhage after stereotactic electrode placement Journal of neurosurgery, 2007; 107(5): 998-1003.
Pouratian Nader, Prevedello Daniel M, Jagannathan Jay, Lopes M Beatriz, Vance Mary Lee, Laws Edward R Outcomes and management of patients with Cushing's disease without pathological confirmation of tumor resection after transsphenoidal surgery The Journal of clinical endocrinology and metabolism, 2007; 92(9): 3383-8.
Sansur Charles A, Pouratian Nader, Dumont Aaron S, Schiff David, Shaffrey Christopher I, Shaffrey Mark E Part II: spinal-cord neoplasms--primary tumours of the bony spine and adjacent soft tissues The lancet oncology, 2007; 8(2): 137-47.
Pouratian Nader, Asthagiri Ashok, Jagannathan Jay, Shaffrey Mark E, Schiff David, Schiff David Surgery Insight: the role of surgery in the management of low-grade gliomas Nature clinical practice. Neurology, 2007; 3(11): 628-39.
Pouratian Nader, Gasco Jaime, Sherman Jonathan H, Shaffrey Mark E, Schiff David Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas Journal of neuro-oncology, 2007; 82(3): 281-8.
Oskouian Rod J, Shaffrey Christopher I, Whitehill Richard, Sansur Charles A, Pouratian Nader, Kanter Adam S, Asthagiri Ashok R, Dumont Aaron S, Sheehan Jason P, Elias W Jeffrey, Shaffrey Mark E Anterior stabilization of three-column thoracolumbar spinal trauma Journal of neurosurgery. Spine, 2006; 5(1): 18-25.
Pouratian Nader Blood flow affects light transmission but its impact on NIRS remains unclear NeuroImage, 2006; 33(1): 11-2.
Guiou Michael, Sheth Sameer, Nemoto Masahito, Walker Melissa, Pouratian Nader, Ba Alyssa, Toga Arthur W Cortical spreading depression produces long-term disruption of activity-related changes in cerebral blood volume and neurovascular coupling Journal of biomedical optics, 2006; 10(1): 11004.
Pouratian Nader, Sheehan Jason, Jagannathan Jay, Laws Edward R, Steiner Ladislau, Vance Mary L Gamma knife radiosurgery for medically and surgically refractory prolactinomas Neurosurgery, 2006; 59(2): 255-66; discussion 255-66.
Crowley R Webster, Pouratian Nader, Sheehan Jason P Gamma knife surgery for glioblastoma multiforme Neurosurgical focus, 2006; 20(4): E17.
Elias W Jeffrey, Pouratian Nader, Oskouian Rod J, Schirmer Bruce, Burns Ted Peroneal neuropathy following successful bariatric surgery. Case report and review of the literature Journal of neurosurgery, 2006; 105(4): 631-5.
Sheehan Jason, Eischeid Anne, Saunders Randi, Pouratian Nader Potentiation of neurite outgrowth and reduction of apoptosis by immunosuppressive agents: implications for neuronal injury and transplantation Neurosurgical focus, 2006; 20(5): E9.
Sheehan Jason P, Jagannathan Jay, Pouratian Nader, Steiner Ladislau Stereotactic radiosurgery for pituitary adenomas: a review of the literature and our experience Frontiers of hormone research, 2006; 34(4): 185-205.
Sheth Sameer A, Nemoto Masahito, Guiou Michael, Walker Melissa, Pouratian Nader, Hageman Nathan, Toga Arthur W Columnar specificity of microvascular oxygenation and volume responses: implications for functional brain mapping The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004; 24(3): 634-41.
Cannestra Andrew F, Pouratian Nader, Forage James, Bookheimer Susan Y, Martin Neil A, Toga Arthur W Functional magnetic resonance imaging and optical imaging for dominant-hemisphere perisylvian arteriovenous malformations Neurosurgery, 2004; 55(4): 804-12; discussion 812-4.
Nemoto Masahito, Sheth Sameer, Guiou Michael, Pouratian Nader, Chen James W Y, Toga Arthur W Functional signal- and paradigm-dependent linear relationships between synaptic activity and hemodynamic responses in rat somatosensory cortex The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004; 24(15): 3850-61.
Sheth Sameer A, Nemoto Masahito, Guiou Michael, Walker Melissa, Pouratian Nader, Toga Arthur W Linear and nonlinear relationships between neuronal activity, oxygen metabolism, and hemodynamic responses Neuron, 2004; 42(2): 347-55.
Pouratian Nader, Cannestra Andrew F, Bookheimer Susan Y, Martin Neil A, Toga Arthur W Variability of intraoperative electrocortical stimulation mapping parameters across and within individuals Journal of neurosurgery, 2004; 101(3): 458-66.
Pouratian Nader, Sheth Sameer, Bookheimer Susan Y, Martin Neil A, Toga Arthur W Applications and limitations of perfusion-dependent functional brain mapping for neurosurgical guidance Neurosurgical focus, 2003; 15(1): E2.
Pouratian Nader, Bookheimer Susan Y, Rubino Gregory, Martin Neil A, Toga Arthur W Category-specific naming deficit identified by intraoperative stimulation mapping and postoperative neuropsychological testing. Case report Journal of neurosurgery, 2003; 99(1): 170-6.
Sheth Sameer, Nemoto Masahito, Guiou Michael, Walker Melissa, Pouratian Nader, Toga Arthur W Evaluation of coupling between optical intrinsic signals and neuronal activity in rat somatosensory cortex NeuroImage, 2003; 19(3): 884-94.
Pouratian Nader, Sheth Sameer A, Martin Neil A, Toga Arthur W Shedding light on brain mapping: advances in human optical imaging Trends in neurosciences, 2003; 26(5): 277-82.
Pouratian Nader, Kassell Neal F, Dumont Aaron S Update on management of intracerebral hemorrhage Neurosurgical focus, 2003; 15(4): E2.
Pouratian Nader, Cannestra Andrew F, Martin Neil A, Toga Arthur W Intraoperative optical intrinsic signal imaging: a clinical tool for functional brain mapping Neurosurgical focus, 2002; 13(4): e1.
Ba Alyssa M, Guiou Michael, Pouratian Nader, Muthialu Arpitha, Rex David E, Cannestra Andrew F, Chen James W Y, Toga Arthur W Multiwavelength optical intrinsic signal imaging of cortical spreading depression Journal of neurophysiology, 2002; 88(5): 2726-35.
Pouratian Nader, Sicotte Nancy, Rex David, Martin Neil A, Becker Donald, Cannestra Andrew F, Toga Arthur W Spatial/temporal correlation of BOLD and optical intrinsic signals in humans Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 2002; 47(4): 766-76.
Blood Anne J, Pouratian Nader, Toga Arthur W Temporally staggered forelimb stimulation modulates barrel cortex optical intrinsic signal responses to whisker stimulation Journal of neurophysiology, 2002; 88(1): 422-37.
Pouratian Nader, Bookheimer Susan Y, Rex David E, Martin Neil A, Toga Arthur W Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations Neurosurgical focus, 2002; 13(4): e4.
Pouratian Nader, Bookheimer Susan Y, Rex David E, Martin Neil A, Toga Arthur W Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations Journal of neurosurgery, 2002; 97(1): 21-32.